Deutsch
 
Benutzerhandbuch Datenschutzhinweis Impressum Kontakt
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT

Freigegeben

Zeitschriftenartikel

Cram Selectivity in the Reaction of 2-Phenylpropanal with Alkyllithium Reagents: Myth and Reality

MPG-Autoren
/persons/resource/persons58919

Reetz,  Manfred T.
Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

Stanchev,  Stephan
Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

Haning,  Helmut
Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

Externe Ressourcen
Es sind keine Externen Ressourcen verfügbar
Volltexte (frei zugänglich)
Es sind keine frei zugänglichen Volltexte verfügbar
Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Reetz, M. T., Stanchev, S., & Haning, H. (1992). Cram Selectivity in the Reaction of 2-Phenylpropanal with Alkyllithium Reagents: Myth and Reality. Tetrahedron, 48(33), 6813-6820. doi:10.1016/S0040-4020(01)89872-0.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0023-CA54-3
Zusammenfassung
The reaction of racemic 2-phenylpropanal with methyl- and n-butyllithium was studied in detail. Factors such as temperature, solvent, rate of addition, presence of salts, scale-up and source of reagents were carefully examined. Cram-selectivities of 90 –94% were routinely reached under standard conditions (THF, −78°C), which is significantly higher than previously reported for these classical reactions