Help Privacy Policy Disclaimer
  Advanced SearchBrowse




Journal Article

Are TMEM genes potential candidate genes for panic disorder?


Erhardt,  Angelika
Dept. Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available

Gregersen, N. O., Buttenschon, H. N., Hedemand, A., Dahl, H. A., Kristensen, A. S., Clementsen, B., et al. (2014). Are TMEM genes potential candidate genes for panic disorder? PSYCHIATRIC GENETICS, 24(1), 37-41. doi:10.1097/YPG.0000000000000022.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0026-ADAC-4
We analysed single nucleotide polymorphisms in two transmembrane genes (TMEM98 and TMEM132E) in panic disorder (PD) patients and control individuals from the Faroe Islands, Denmark and Germany. The genes encode single-pass membrane proteins and are located within chromosome 17q11.2-q12, a previously reported candidate region for PD. Three single nucleotide polymorphisms (rs887231, rs887230 and rs4795942) located upstream and within TMEM132E showed a nominal significant association with PD primarily in the Danish cohort. No nominal significant associations were observed between TMEM98 and PD. Our data indicate that TMEM132E might contribute moderately towards the risk of developing PD.