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Characteristics of initial fearful spells and their associations with DSM-IV panic attacks and panic disorder in adolescents and young adults from the community

MPG-Autoren
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Wittchen,  Hans-Ulrich
Max Planck Institute of Psychiatry, Max Planck Society;

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Lieb,  Roselind
Max Planck Institute of Psychiatry, Max Planck Society;

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Zitation

Asselmann, E., Pane-Farre, C., Isensee, B., Wittchen, H.-U., Lieb, R., Hofler, M., et al. (2014). Characteristics of initial fearful spells and their associations with DSM-IV panic attacks and panic disorder in adolescents and young adults from the community. JOURNAL OF AFFECTIVE DISORDERS, 165, 95-102. doi:10.1016/j.jad.2014.04.045.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0024-60FE-D
Zusammenfassung
Background: Few studies examined characteristics of initial fearful spells (FS) or panic attacks (PA) and their relation to DSM-IV PA and panic disorder (PD). Methods: A community sample of adolescents and young adults (N=3021) was followed up in 4 waves (T0-T3) over up to 10 years. FS, PA, and PD were assessed at each wave using the DSM-IV/M-CIDI. Characteristics of the initial FS/PA including perceived reasons/triggers, appraisal, duration, and behavioral/emotional consequences of the initial FS/PA were retrospectively assessed at T1 and T2 in those reporting the experience of lifetime FS or PA at these waves (N=363). Multinomial logistic regressions adjusted for sex and age were used to reveal associations of initial FS/PA characteristics (aggregated data from T1 and 12) with PA only (N-88) and PD (N=62; lifetime incidences cumulated across assessment waves) (reference group: No PA/PD). Results: Alcohol consumption, drugs/medication, and physical illness as perceived reasons for the initial FS/PA were associated with PA-only (OR 2.46-5.44), while feelings of depression, feelings of anxiety, and having always been anxious/nervous as perceived reasons for the initial FS/PA, appraising the initial FS/PA as terrible and long-term irritating/burdensome, subsequent feelings of depression, subsequent avoidance, and subsequent consumption of medication, alcohol, or drugs were associated with PD (OR 2.64-4.15). A longer duration until "feeling okay again" was associated with both PA-only (OR=1.29 per category) and PD (OR=1.63). Limitations: Initial FS/PA characteristics were necessarily assessed retrospectively by self-report only. Thus, our data might be subject to recall/evaluation biases. Aggregated data were used and strictly prospective-longitudinal studies are necessary that replicate our findings. Conclusion: Assessing initial FS/PA characteristics might be useful to identify individuals at increased risk for more severe panic pathology. (C) 2014 Elsevier B.V. All rights reserved.