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Total synthesis of amphidinolide T4

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Fürstner,  Alois
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Aïssa,  Christophe
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Riveiros,  Ricardo
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Ragot,  Jacques
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Citation

Fürstner, A., Aïssa, C., Riveiros, R., & Ragot, J. (2002). Total synthesis of amphidinolide T4. Angewandte Chemie International Edition, 41(24), 4763-4766. doi:10.1002/anie.200290042.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0024-C2DD-D
Abstract
Organometallic chemistry in general and catalysis in particular are used in the first total synthesis of amphidinolide T4 (see scheme); a prototype member of a series of macrolide antibiotics of marine origin with rings containing an odd number of carbon atoms.