Diffusion-weighted imaging in acute stroke - A tool of uncertain value?

Fiehler, J.; Fiebach, J. B.; Gass, A.; Hoehn, Mathias; Kucinski, T.; Neumann-Haefelin, Tobias,; Schellinger, P. D.; Siebler, M.; Villringer, A.; Rother, J.

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Diffusion-weighted imaging in acute stroke - A tool of uncertain value?

MPS-Authors

/persons/resource/persons147197

Hoehn, Mathias
In-vivo-NMR, Research Groups, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Fiehler, J., Fiebach, J. B., Gass, A., Hoehn, M., Kucinski, T., Neumann-Haefelin, T., et al. (2002). Diffusion-weighted imaging in acute stroke - A tool of uncertain value? Cerebrovascular Diseases, 14(3-4), 187-196.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0026-D3F9-E

Abstract

The concept of a mismatch between the lesion volume in diffusion- and perfusion-weighted magnetic resonance imaging (MRI) indicating 'tissue at risk of infarction' is based on the assumption that tissue with diffusion slowing in diffusion- weighted MRI (DWI) or decreased values of the apparent diffusion coefficient represents irreversibly damaged tissue. Recent experimental as well as clinical studies, however, have shown that tissue with diffusion slowing may well normalize if the hypoperfusion is moderate or transient. We will interpret these findings in the light of experimental data and suggest a way for the interpretation of different time courses of lesion development in DWI within a clinical MRI protocol. MR stroke imaging delivers important information in acute stroke, particularly in defining the 'tissue at risk of infarction'.