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Journal Article

Aortic pulse wave velocities using real-time phase-contrast MRI.

MPS-Authors
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Joseph,  A. A.
Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society;

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Merboldt,  K. D.
Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society;

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Frahm,  J.
Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society;

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Citation

Joseph, A. A., Fasshauer, M., Merboldt, K. D., & Frahm, J. (2015). Aortic pulse wave velocities using real-time phase-contrast MRI. The Open Medical Imaging Journal, 9, 9-14. doi:10.2174/1874347101509010009.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0026-CE41-E
Abstract
Purpose: To evaluate aortic pulse wave velocities obtained by real-time phase-contrast (PC) MRI in comparison to cine PC MRI. Methods: Real-time PC MRI of eight healthy volunteers employed highly undersampled radial FLASH sequences and phase-sensitive image reconstructions by regularized nonlinear inversion (NLINV) at 40 ms temporal resolution and 1.3 mm in-plane resolution. Pulse wave velocities were analyzed for combinations of 2, 3 and 4 locations of aortic flow using time-to-upslope and cross-correlation methods. Results: For the time-to-upslope analysis mean pulse wave velocities ranged from 3.5 to 3.9 m s-1 for real-time PC MRI and from 3.5 to 3.8 m s-1 for cine PC MRI. A cross-correlation analysis of the same data resulted in 2.9 to 3.3 m s-1 and 3.3 to 3.7 m s-1, respectively. Conclusion: Real-time PC MRI determined aortic pulse wave velocities from single cardiac cycles in close correspondence to values obtained by cine PC MRI.