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Synthesis of diverse glycosylphosphatidylinositol glycans from toxoplasma gondii and their application as vaccines and diagnostics

MPS-Authors
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Azzouz,  Nahid
Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Götze,  Sebastian
Daniel Varón Silva, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Seeberger,  Peter H.
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Varón Silva,  Daniel
Daniel Varón Silva, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Tsai,  Yu-Hsuan
Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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2156736.pdf
(Publisher version), 3MB

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Citation

Azzouz, N., Götze, S., Seeberger, P. H., Varón Silva, D., & Tsai, Y.-H.(2014). Synthesis of diverse glycosylphosphatidylinositol glycans from toxoplasma gondii and their application as vaccines and diagnostics.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0027-1340-A
Abstract
The present invention relates to the synthesis of GPI-related surface antigens of the parasite Toxoplasma gondii (T. gondii) and the resulting products obtained. These synthetic compounds are suitable for diagnosis of toxoplasmosis, as well as vaccine against toxoplasmosis, a diseases caused by infection with T. gondii.