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Book Chapter

Phase Variations in fMRI Time Series Analysis: Friend or Foe?

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Hagberg,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Hagberg, G., & Tuzzi, E. (2014). Phase Variations in fMRI Time Series Analysis: Friend or Foe? In T. Papageorgiou, G. Christopoulos, & S. Smirnakis (Eds.), Advanced Brain Neuroimaging Topics in Health and Disease: Methods and Applications (pp. 81-113). Rijeka, Croatia: InTech.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0027-80C7-0
Abstract
Functional MRI studies (fMRI) are based on the blood-oxygenation-level-dependent effect (BOLD) that arises in brain areas where neuronal activity takes place (Ogawa et al., 1990, 1993). BOLD induces changes in the local magnetic susceptibility and these can be measured by Gradient Echo (GE) Echo-Planar-Imaging (EPI). The fMRI signal thus observed consists of a complex value, which can be subdivided into a magnitude and a phase value, but in most fMRI studies the phase signal is discarded and only the magnitude changes are used to detect the activated brain areas.