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Journal Article

Chromatin chemistry goes cellular.

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Fischle,  W.
Research Group of Chromatin Biochemistry, MPI for biophysical chemistry, Max Planck Society;

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Citation

Fischle, W., Schwarzer, D., & Mootz, H. D. (2015). Chromatin chemistry goes cellular. Nature Chemistry, 7(5), 371-373. doi:10.1038/nchem.2249.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0027-830A-4
Abstract
Analysing post-translational modifications of histone proteins as they occur within chromatin is challenging due to their large number and chemical diversity. A major step forward has now been achieved by using split intein chemistry to engineer functionalized histones within cells.