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Journal Article

MTERF1 gives mtDNA an unusual twist

MPS-Authors

Gustafsson,  Claes M
Max Planck Society;

Larsson,  Nils-Göran
Max Planck Society;

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Citation

Gustafsson, C. M., & Larsson, N.-G. (2010). MTERF1 gives mtDNA an unusual twist. Cell Metab, 12(1), 3-4.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0028-58F6-1
Abstract
Expression of mtDNA is critical for biogenesis of the oxidative phosphorylation system, but the regulatory processes are poorly understood. Recent work in Cell (Yakubovskaya et al., 2010) reports a novel DNA-binding fold in mitochondrial transcription termination factor 1 (MTERF1), which causes unwinding and base eversion at its target mtDNA sequence.