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Journal Article

Complex I: a complex gateway to the powerhouse

MPS-Authors

Sterky, Fredrik Hansson
Max Planck Society;

Larsson, Nils-Göran
Max Planck Society;

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Citation

Sterky, F. H., & Larsson, N.-G. (2008). Complex I: a complex gateway to the powerhouse. Cell Metab, 7(4), 278-279.

Abstract

Complex I, the main entry point for electrons to the respiratory chain, is of critical importance for cellular energy homeostasis. In this issue of Cell Metabolism, Kruse and coworkers (2008) describe the first mouse knockout for a complex I structural subunit, thus advancing our understanding of complex I in disease.