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Aptamer-based affinity labeling of proteins

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Citation

Vinkenborg, J. L., Mayer, G., & Famulok, M. (2012). Aptamer-based affinity labeling of proteins. Angewandte Chemie (International ed.in English), 51(36), 9176-80. doi:10.1002/anie.201204174.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0028-63FF-D
Abstract
A most able label: Labeled aptamers can be cross-linked to their target structures in a light-dependent and highly specific manner as a result of a new strategy termed aptamer-based affinity labeling (ABAL) of proteins. The aptamer-protein complexes can be enriched in vitro, from a cellular lysate and from the surface of living cells, opening new ways to study aptamer interactions in biological contexts.