Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates

Ackermann, D.; Rasched, G.; Verma, S.; Schmidt, T. L.; Heckel, A.; Famulok, M.

doi:10.1039/c0cc00390e

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Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates

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http://www.ncbi.nlm.nih.gov/pubmed/20473448
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http://pubs.rsc.org/en/content/articlepdf/2010/cc/c0cc00390e
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Ackermann, D., Rasched, G., Verma, S., Schmidt, T. L., Heckel, A., & Famulok, M. (2010). Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates. Chemical Communications, 46(23), 4154-6. doi:10.1039/c0cc00390e.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0028-6442-9

Abstract

The assembly of double-stranded (ds) DNA nanocircles both by hybridization with branched oligodeoxynucleotides (ODNs) and by intercalation was analyzed by atomic force microscopy (AFM). Branched ODNs ligated to single-stranded (ss) gap regions of dsDNA nanocircles led to defined, dumbbell-shaped architectures. ODNs containing an aromatic intercalator yielded oligomeric aggregates.