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Journal Article

Large Tailed Spindle Viruses of Archaea: a New Way of Doing Viral Business

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Bollschweiler,  Daniel
Baumeister, Wolfgang / Molecular Structural Biology, Max Planck Institute of Biochemistry, Max Planck Society;

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Engelhardt,  Harald
Baumeister, Wolfgang / Molecular Structural Biology, Max Planck Institute of Biochemistry, Max Planck Society;

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Lawrence,  C. Martin
Baumeister, Wolfgang / Molecular Structural Biology, Max Planck Institute of Biochemistry, Max Planck Society;

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Citation

Hochstein, R., Bollschweiler, D., Engelhardt, H., Lawrence, C. M., & Young, M. (2015). Large Tailed Spindle Viruses of Archaea: a New Way of Doing Viral Business. JOURNAL OF VIROLOGY, 89(18), 9146-9149. doi:10.1128/JVI.00612-15.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0028-9594-D
Abstract
Viruses of Archaea continue to surprise us. Archaeal viruses have revealed new morphologies, protein folds, and gene content. This is especially true for large spindle viruses, which infect only Archaea. We present a comparison of particle morphologies, major coat protein structures, and gene content among the five characterized large spindle viruses to elucidate defining characteristics. Structural similarities and a core set of genes support the grouping of the large spindle viruses into a new superfamily.