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Journal Article

Can proteomics-based diagnostics aid clinical psychiatry?


Filiou,  Michaela D.
Dept. Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Max Planck Society;

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Filiou, M. D. (2015). Can proteomics-based diagnostics aid clinical psychiatry? Proteomics Clinical Applications, SI, 9(9-10), 885-888. doi:10.1002/prca.201400144.

Cite as: http://hdl.handle.net/11858/00-001M-0000-0029-B086-C
Despite major advances in infrastructure and instrumentation, proteomics-driven translational applications have not yet yielded the results that the scientific community has envisaged. In this viewpoint, the perspective of proteomics-based diagnostics in the field of clinical psychiatry is explored. The challenges that proteomics faces in the context of translational approaches are outlined and directions toward a successful clinical implementation are provided. Additional challenges that psychiatric disorders pose for clinical proteomics are highlighted and the potential of proteomics-based, blood tests for psychiatric disorders is being assessed. Proteomics offers a valuable toolkit for clinical translation that needs to be handled in a pragmatic manner and with realistic expectations.