Picosecond Infrared Laser (PIRL) Scalpel: Achieving the Fundamental Limits to 
Minimally Invasive Surgery and Biodiagnostics

Miller, R. J. Dwayne

doi:10.1364/ASSL.2015.AF2A.1

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Picosecond Infrared Laser (PIRL) Scalpel: Achieving the Fundamental Limits to Minimally Invasive Surgery and Biodiagnostics

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Miller, R. J. Dwayne
Miller Group, Atomically Resolved Dynamics Department, Max Planck Institute for the Structure and Dynamics of Matter, Max Planck Society;
Department of Chemistry and Physics, 80 St. George Street, University of Toronto, Toronto, Ontario M5S 3H6, Canada;

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http://dx.doi.org/10.1364/ASSL.2015.AF2A.1
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Citation

Miller, R. J. D. (2015). Picosecond Infrared Laser (PIRL) Scalpel: Achieving the Fundamental Limits to Minimally Invasive Surgery and Biodiagnostics. In Advanced Solid State Lasers. Optical Society of America. doi:10.1364/ASSL.2015.AF2A.1.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0029-5D39-7

Abstract

A new mechanism has been discovered that completely arrests nucleation growth and eliminates associated shock wave damage to adjacent tissue with effectively no scar tissue formation. The ablation process selectively excites water to act as the propellant driving the ablation process effectively faster than even collisional energy transfer/fragmentation to the constituent proteins. This process has been found to provide intact molecular signatures for in situ biodiagnostics. Both surgery at the single cell level without scar tissue formation and near attomolar protein detection without labelling has been achieved.