The mystery of the fusion pore.

Sharma, S.; Lindau, M.

doi:10.1038/nsmb.3157

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Journal Article

The mystery of the fusion pore.

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Sharma, S.
Research Group of Nanoscale Cell Biology, MPI for Biophysical Chemistry, Max Planck Society;

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Lindau, M.
Research Group of Nanoscale Cell Biology, MPI for Biophysical Chemistry, Max Planck Society;

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http://www.nature.com/nsmb/journal/v23/n1/pdf/nsmb.3157.pdf
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2243125_Suppl.pdf
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Citation

Sharma, S., & Lindau, M. (2016). The mystery of the fusion pore. Nature Structural and Molecular Biology, 23(1), 5-6. doi:10.1038/nsmb.3157.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0029-61A4-7

Abstract

Release of neurotransmitters occurs by opening of a fusion pore in a manner thought to be mediated by SNARE proteins, but whether the fusion pore is a lipidic or a proteinaceous structure is controversial. A new study using very small nanodiscs shows that it is both.