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Journal Article

The mystery of the fusion pore.

MPS-Authors
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Sharma,  S.
Research Group of Nanoscale Cell Biology, MPI for Biophysical Chemistry, Max Planck Society;

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Lindau,  M.
Research Group of Nanoscale Cell Biology, MPI for Biophysical Chemistry, Max Planck Society;

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Supplementary Material (public)

2243125_Suppl.pdf
(Supplementary material), 55KB

Citation

Sharma, S., & Lindau, M. (2016). The mystery of the fusion pore. Nature Structural and Molecular Biology, 23(1), 5-6. doi:10.1038/nsmb.3157.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0029-61A4-7
Abstract
Release of neurotransmitters occurs by opening of a fusion pore in a manner thought to be mediated by SNARE proteins, but whether the fusion pore is a lipidic or a proteinaceous structure is controversial. A new study using very small nanodiscs shows that it is both.