English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Rekonstitution biologischer Selbstorganisation in vitro

MPS-Authors
/persons/resource/persons145387

Kretschmer,  Simon
Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society;

/persons/resource/persons15815

Schwille,  Petra
Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society;

External Resource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Kretschmer, S., & Schwille, P. (2015). Rekonstitution biologischer Selbstorganisation in vitro. Biospektrum, 21(2), 148-150. doi:10.1007/s12268-015-0550-6.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0029-AA09-F
Abstract
The Escherichia coli Min proteins select the cell middle for division by oscillating between the cell poles where they inhibit the divisome protein FtsZ. Reconstitution of Min proteins on a lipid membrane in vitro yields their self-organization into surface waves. In biomimetic compartments, pole-to-pole oscillations can be obtained which direct FtsZ to the middle. This establishes bottom-up synthetic biology as a promising approach to reconstitute complex dynamics and spatial cues in vitro.