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Meeting Abstract

Ultra-short TE STEAM improves hepatic lipid quantification and profiling at 7T

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Chadzynski,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Gajdošík, M., Chadzynski, G., Mlynarik, V., Chmelík, M., Bogner, W., Valkovic, L., et al. (2015). Ultra-short TE STEAM improves hepatic lipid quantification and profiling at 7T. In 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015).


Cite as: http://hdl.handle.net/11858/00-001M-0000-002A-45C4-A
Abstract
Previous 1H MRS measurements in the brain have demonstrated advantages of ultra-short TE at ultra-high fields. Besides higher SNR, T2 relaxation and J-modulation effects in the spectra can be minimized. This is of particular importance in the liver tissue, where both effects along with iron deposition have to be taken into account. The STEAM with TE=6ms provided higher SNR and reproducibility for precise estimation of HCL. Furthermore the high spectral resolution at 7T with sufficient CRLB´s of single lipid resonances highlights the potential of this sequence to be used in advanced studies of hepatic lipid profiles in vivo.