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Choline: a differential marker of glutamatergic neurotransmission?

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Henning,  A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Henning, A., Grimm, S., Seifritz, E., & Scheidegger, M. (2015). Choline: a differential marker of glutamatergic neurotransmission?. Poster presented at 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, Canada.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002A-461C-F
Abstract
In this work, we demonstrate that the cerebral Cho concentration is related to adaptive changes in neurotransmitter and more specifically glutamate secretion. To this we used the NMDA-receptor antagonist ketamine as a tool compound, which was previously shown by invasive methods to largely increase synaptic glutamate release.