T2 estimation of downfield metabolites in human brain at 7T

Fichtner, ND; Henning, A; Zoelch, N; Boesch, C; Kreis, R

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T2 estimation of downfield metabolites in human brain at 7T

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Henning, A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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http://www.ismrm.org/15/program_files/MonTP04.htm
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Citation

Fichtner, N., Henning, A., Zoelch, N., Boesch, C., & Kreis, R. (2015). T2 estimation of downfield metabolites in human brain at 7T. Poster presented at 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, Canada.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002A-4626-8

Abstract

The upfield part of the spectrum has thus far been well-characterized using magnetic resonance spectroscopy; however, the downfield part at 5-10ppm remains less so, particularly in humans. This work aims to improve metabolite characterization by calculating the T2’s of peaks downfield in grey matter at 7 T. We fitted downfield spectra to a heuristic model and obtained T2’s for several peaks of interest; the T2’s are all fairly similar, but significantly shorter than those reported for upfield peaks in the brain, which are approximately 70ms or longer depending on the structure.