Eyes without a ribbon.

Moser, T.

doi:10.15252/embj.201694205

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Eyes without a ribbon.

MPS-Authors

/persons/resource/persons15548

Moser, T.
Research Group of Synaptic Nanophysiology, MPI for Biophysical Chemistry, Max Planck Society;

External Resource

http://onlinelibrary.wiley.com/doi/10.15252/embj.201694205/full
(Publisher version)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Moser, T. (2016). Eyes without a ribbon. EMBO Journal, 35(10), 1018-1020. doi:10.15252/embj.201694205.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002A-E473-8

Abstract

Eye and ear employ specialized glutamatergic synapses that feature an elaborate electron-dense projection-the synaptic ribbon. Despite major efforts, the function of the synaptic ribbon has remained enigmatic, because its brick-stone-like core-component RIBEYE has remained hard to crack genetically. In an elegant study, Maxeiner et al (2016) genetically deleted RIBEYE in mice. This abolished retinal ribbons and impaired exocytosis at the presynaptic active zone of bipolar cells.