User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse




Journal Article

C–H Functionalization on Carbohydrates


Frihed,  Tobias Gylling
Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Ressource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available

Frihed, T. G., Bols, M., & Pedersen, C. M. (2016). C–H Functionalization on Carbohydrates. European Journal of Organic Chemistry, (16), 2740-2756. doi:10.1002/ejoc.201600121.

Cite as: http://hdl.handle.net/11858/00-001M-0000-002A-F408-E
Functionalization of C–H bonds has received significant attention in organic chemistry during the last decade and it is still a “hot” topic. In particular, C–H modification of natural products has benefitted from this development. Carbohydrates are densely functionalized natural products, and methods for their functionalization are therefore very attractable. This review presents methods from the last five decades and gives an overview of the developments in C–H functionalization of carbohydrates. It covers all methods in which a C–H bond is broken: from radical abstractions and carbene insertion to new metal-catalyzed approaches. The review systematically covers the carbohydrates position-by-position and hence gives a quick overview.