Selective Aromatic C-H Hydroxylation Enabled by η6-Coordination to Iridium(III)

D'Amato, Erica M.; Neumann, Constanze N.; Ritter, Tobias

doi:10.1021/acs.organomet.5b00731

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Selective Aromatic C-H Hydroxylation Enabled by η⁶-Coordination to Iridium(III)

MPS-Authors

There are no MPG-Authors in the publication available

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

D'Amato, E. M., Neumann, C. N., & Ritter, T. (2015). Selective Aromatic C-H Hydroxylation Enabled by η⁶-Coordination to Iridium(III). Organometallics, 34(18), 4626-4631. doi:10.1021/acs.organomet.5b00731.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002B-9FF8-1

Abstract

We report an aromatic C–H hydroxylation protocol in which the arene is activated through η⁶-coordination to an iridium(III) complex. η⁶-Coordination of the arene increases its electrophilicity and allows for high positional selectivity of hydroxylation at the site of least electron density. Through investigation of intermediate η⁵-cyclohexadienyl adducts and arene exchange reaction, we evaluate incorporation of arene π-activation into a catalytic cycle for C–H functionalization.