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Journal Article

Structure determination of transient transcription complexes.

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Cramer,  P.
Department of Molecular Biology, MPI for Biophysical Chemistry, Max Planck Society;

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Cramer, P. (2016). Structure determination of transient transcription complexes. Biochemical Society Transactions, 44(4), 1177-1182. doi:10.1042/BST20160079.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002B-258D-A
Abstract
The determination of detailed 3D structures of large and transient multicomponent complexes remains challenging. Here I describe the approaches that were used and developed by our laboratory to achieve structure solution of eukaryotic transcription complexes. I hope this collection serves as a resource for structural biologists seeking solutions for difficult structure determination projects.