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Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry

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Ritter,  Tobias
Department of Chemistry and Chemical Biology, Harvard University;
Research Department Ritter, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Citation

Regalado, E. L., Kozlowski, M. C., Curto, J. M., Ritter, T., Campbell, M. G., Mazzotti, A. R., et al. (2014). Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry. Organic & Biomolecular Chemistry, 12(14), 2161-2166. doi:10.1039/c3ob42195c.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002B-858D-2
Abstract
The use of state-of-the-art separation tools from the pharmaceutical industry for addressing intractable separation problems from academic synthetic chemistry is evaluated, showing fast and useful results for the resolution of complex mixtures, separation of closely related components, visualization of difficult to detect compounds and purification of synthetic intermediates. Some recommendations for potential near term deployment of separation tools within academia and the evolution of next generation separation technologies are discussed.