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Fold-Hopf bursting in a model for calcium signal transduction

MPS-Authors
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Brusch,  L.
Max Planck Institute for the Physics of Complex Systems, Max Planck Society;

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Or-Guil,  M.
Max Planck Institute for the Physics of Complex Systems, Max Planck Society;

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Bär,  M.
Max Planck Institute for the Physics of Complex Systems, Max Planck Society;

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Citation

Brusch, L., Lorenz, W., Or-Guil, M., Bär, M., & Kummer, U. (2002). Fold-Hopf bursting in a model for calcium signal transduction. Zeitschrift für Physikalische Chemie-International Journal of Research in Physical Chemistry & Chemical Physics, 216(4), 487-497. Retrieved from http://www.oldenbourg.de/verlag/z-phys-chem/.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002B-387B-6
Abstract
We study a recent model for calcium Signal transduction. This model displays spiking, bursting and chaotic oscillations in accordance with experimental results. We calculate bifurcation diagrams and study the bursting behaviour in detail. This behaviour is classified according to the dynamics of separated slow and fast subsystems. It is shown to be of the Fold-Hopf type, a type which was previously only described in the context of neuronal systems, but not in the context of signal transduction in the cell.