Isotope-Ratio-Monitoring Liquid Chromatography Mass Spectrometry (IRM-LCMS): 
First results from a moving wire interface system

Brand, Willi A.; Dobberstein, P.

doi:10.1080/10256019608036320

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Isotope-Ratio-Monitoring Liquid Chromatography Mass Spectrometry (IRM-LCMS): First results from a moving wire interface system

MPS-Authors

There are no MPG-Authors in the publication available

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Brand, W. A., & Dobberstein, P. (1996). Isotope-Ratio-Monitoring Liquid Chromatography Mass Spectrometry (IRM-LCMS): First results from a moving wire interface system. Isotopes in Environmental and Health Studies, 32(2-3), 275-283. doi:10.1080/10256019608036320.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002B-4898-3

Abstract

A Liquid Chromatography-Combustion (LC-C) Interface, based on a moving wire technique, has been built and tested. The LC effluent is deposited onto a transport wire, which carries the sample through solvent evaporation and combustion ovens. CO(2) from the combustion step is analysed in an isotope ratio mass spectrometer. Performance of the interface was tested by loop injections of sucrose and glucose into a liquid flow of methanol/water (80/20). Accuracy and precision of δ(13)C(PDB) < 1‰ was achieved for sample concentrations > 500 ng/ul (5μl loop), sufficient for studies at natural isotope ratios. In case of (13)C tracer applications the detection limit was determined to be about 20 pg carbon tracer (on wire).