English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse
  1. Start / 
  2. Item Summary

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

NMR spectroscopy in andrology: research uses and possible clinical applications

MPS-Authors
/persons/resource/persons93660

Kalbitzer,  HR
Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Rohr, G., Eggert-Kruse, W., & Kalbitzer, H. (1995). NMR spectroscopy in andrology: research uses and possible clinical applications. International journal of andrology, 18(Suppl. 2), 12-19. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/8719853.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002B-4F7A-B
Abstract
Research uses and possible clinical applications of NMR spectroscopy are considered. By monitoring extracts of testes using 31P-NMR spectroscopy, detailed analysis of high-energy phosphates, or pathways such as phospholipid biosynthesis or glycolysis, is possible. By using in-vivo 31P NMR spectroscopy of testes in animal experiments it has proved possible to discriminate non-invasively between experimentally impaired and control testes. It has been demonstrated in several human studies that discrimination between normal testes and those with impaired spermatogenesis and obstruction is possible by non-invasive NMR spectroscopy. In studies of semen, seminal plasma or spermatozoa, NMR spectroscopy is of high experimental value for analysis of sample composition, the kinetics of metabolites or the structure of single components, but clinical applications have not yet been clearly defined.