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A New Vampire Saga: The Molecular Mechanism of T Cell Trogocytosis

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Dopfer,  Elaine Pashupati
Research Group and Chair of Molecular Immunology of the University of Freiburg, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

Minguet,  Susana
Max Planck Society;

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Schamel,  Wolfgang W. A.
Research Group and Chair of Molecular Immunology of the University of Freiburg, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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Citation

Dopfer, E. P., Minguet, S., & Schamel, W. W. A. (2011). A New Vampire Saga: The Molecular Mechanism of T Cell Trogocytosis. Immunity, 35, 151-153.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002B-8DC9-D
Abstract
In the current issue of Immunity, Martínez-Martín et al. (2011) describe the central supramolecular activation cluster (cSMAC) as a site of clathrin-independent T cell receptor (TCR) internalization and trogocytosis. Further, they identify small Rho GTPases TC21 and RhoG as key mediators of these processes.