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Cluster Preface: Challenges of Proline-Based Aminocatalysis

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List,  Benjamin
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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List, B. (2011). Cluster Preface: Challenges of Proline-Based Aminocatalysis. Synlett, (4), 462-463. doi:10.1055/s-0030-1259544.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002B-8820-B
Abstract
During the last eleven years, aminocatalysis, the catalysis of carbonyl transformations via iminium ion and enamine intermediates has become a highly successful and general approach to asymmetric synthesis. There are now several dozens of different ­reaction types with hundreds of variants that are mediated by primary and secondary amine catalysts, of which proline continues to be a privileged motif. This Cluster highlights recent attempts towards solving some of the remaining challenges in the area.