English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Growth of fingerlike protrusions driven by molecular motors

MPS-Authors
There are no MPG-Authors available
External Ressource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Kruse, K., & Sekimoto, K. (2002). Growth of fingerlike protrusions driven by molecular motors. PHYSICAL REVIEW E, 66(3): 031904. doi:10.1103/PhysRevE.66.031904.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002C-5B2B-D
Abstract
The actin cortex is an important part of the motile machinery of a eucaryotic cell. The cortex is steadily reorganized, for example, through the action of molecular motors forming active crosslinks between pairs of actin filaments. Here, the effect of correlations between molecular motors on the induced relative motion of two aligned filaments is investigated. It is found that the average relative velocity between filaments depends nonmonotonically on the motor concentration. Depending on the properties of the filaments' ends, the active interaction between filaments of the same orientation may lead either to a complete overlap or to separation. In addition to pure actin polymerization the active separation of filaments might be involved in the growth of long fingerlike protrusions (filopods).