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Micro-nanostructured protein arrays: a tool for geometrically controlled single ligand presentation

MPG-Autoren
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Aydin,  Daniel
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

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Schwieder,  Marco
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

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Louban,  Ilia
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

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Ulmer,  Jens
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

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Spatz,  Joachim P.
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;
Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany;

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Zitation

Aydin, D., Schwieder, M., Louban, I., Knoppe, S., Ulmer, J., Haas, T. L., et al. (2009). Micro-nanostructured protein arrays: a tool for geometrically controlled single ligand presentation. Small, 5(9), 1014-1018. doi:10.1002/smll.200801219.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0010-3DB0-3
Zusammenfassung
A novel approach for the rapid fabrication of extended areas of micrometer-scaled patches of quasi-hexagonally ordered gold nanoparticle arrays (see image) is presented. The resulting substrates serve as templates for the site-specific immobilization of proteins to gold nanoparticles enabling nanoscopically and microscopically controlled protein deposition.