A return to the pore – dissecting Bacillus thuringiensis toxin mode of action 
via voltage clamp experiments (commentary)

Heckel, David G.

doi:10.1111/febs.13973

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A return to the pore – dissecting Bacillus thuringiensis toxin mode of action via voltage clamp experiments (commentary)

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Heckel, David G.
Department of Entomology, Prof. D. G. Heckel, MPI for Chemical Ecology, Max Planck Society;

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Citation

Heckel, D. G. (2016). A return to the pore – dissecting Bacillus thuringiensis toxin mode of action via voltage clamp experiments (commentary). The FEBS Journal, 283(24), 4458-4461. doi:10.1111/febs.13973.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002C-2A02-3

Abstract

Pore-forming toxins from Bacillus thuringiensis are increasingly used in crop protection, but evolution of resistance in crop pests threatens their continued deployment. A study by Tanaka et al. shows how voltage clamp experiments that quantify pore formation can be used to dissect toxin mode of action, thereby revealing unexpected complexities that could be exploited to counter resistance.