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Journal Article

MRI of "diffusion" in the human brain: New results using a modified CE-FAST sequence.

MPS-Authors
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Merboldt,  K. D.
Research Group of Biomedical NMR, MPI for Biophysical Chemistry, Max Planck Society;

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Bruhn,  H.
Research Group of Biomedical NMR, MPI for Biophysical Chemistry, Max Planck Society;

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Frahm,  J.
Research Group of Biomedical NMR, MPI for Biophysical Chemistry, Max Planck Society;

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Gyngell,  M.L.
Research Group of Biomedical NMR, MPI for Biophysical Chemistry, Max Planck Society;

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Hänicke,  W.
Research Group of Biomedical NMR, MPI for Biophysical Chemistry, Max Planck Society;

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2395257.pdf
(Publisher version), 495KB

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Citation

Merboldt, K. D., Bruhn, H., Frahm, J., Gyngell, M., Hänicke, W., & Deimling, M. (1989). MRI of "diffusion" in the human brain: New results using a modified CE-FAST sequence. Magnetic Resonance in Medicine, 9(3), 423-429. doi:10.1002/mrm.1910090316.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002C-6115-1
Abstract
“Diffusion-weighted” MRI in the normal human brain and in a patient with a cerebral metastasis is demonstrated. The method employed was a modified CE-FAST sequence with imaging times of only 6-10 s using a conventional 1.5-T whole-body MRI system (Siemens Magnetom). As with previous phantom and animal studies, the use of strong gradients together with macroscopic motions in vivo causes unavoidable artifacts in diffusion-weighted images of the human brain. While these artifacts are shown to be considerably reduced by averaging of 8-16 images, the resulting diffusion contrast is compromised by unknown signal losses due to motion.