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Journal Article

Getting a grip on collective cell migration

MPS-Authors
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Das,  Tamal
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;
Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany;

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Spatz,  Joachim P.
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;
Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany;

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Citation

Das, T., & Spatz, J. P. (2016). Getting a grip on collective cell migration. Nature Cell Biology, 18(12), 1265-1267. doi:10.1038/ncb3447.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002C-82E7-C
Abstract
Many cell types in our body move in a collective manner, which requires individual cells to align their movements relative to that of their neighbours. A mechanism is now described in which cadherin-rich protrusions are extended from leading migrating cells and engulfed by follower cells to guide collective migration.