User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse




Journal Article

Ipsi- and contralateral EEG reactions to transcranial magnetic stimulation

There are no MPG-Authors available
External Ressource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available

Komssi, S., Aronen, H. J., Huttunen, J., Kesäniemi, M., Soinne, L., Nikulin, V. V., et al. (2002). Ipsi- and contralateral EEG reactions to transcranial magnetic stimulation. Clinical Neurophysiology, 113(2), 175-184. doi:10.1016/S1388-2457(01)00721-0.

Cite as: http://hdl.handle.net/11858/00-001M-0000-002D-415A-8
Objectives: Transcranial magnetic stimulation (TMS) and high-resolution electroencephalography (EEG) were used to study the spreading of cortical activation in 6 healthy volunteers. Methods: Five locations in the left sensorimotor cortex (within 3 cm2) were stimulated magnetically, while EEG was recorded with 60 scalp electrodes. A frameless stereotactic method was applied to determine the anatomic locus of stimulation and to superimpose the results on magnetic resonance images. Scalp potential and cortical current-density distributions were derived from averaged electroencephalographic (EEG) data. Results: The maxima of the ipsilateral activation were detected at the gyrus precentralis, gyrus supramarginalis, and lobulus parietalis superior, depending on the subject. Activation over the contralateral cortex was observed in all subjects, appearing at 22±2 ms (range 17–28); the maxima were located at the gyrus precentralis, gyrus frontalis superior, and the lobulus parietalis inferior. Contralateral EEG waveforms showed consistent changes when different sites were stimulated: stimulation of the two most medial points evoked the smallest responses fronto-parietally. Conclusions: With the combination of TMS, EEG, and magnetic resonance imaging, an adequate spatiotemporal resolution may be achieved for tracing the intra- and interhemispheric spread of activation in the cortex caused by a magnetic pulse.