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Journal Article

Interaction of insulin with lipid monolayers at the air/solution interface.

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Kozarac,  Z.
Research Group of Molecular Organized Systems, MPI for biophysical chemistry, Max Planck Society;

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Dhathathreyan,  A.
Research Group of Molecular Organized Systems, MPI for biophysical chemistry, Max Planck Society;

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Möbius,  D.
Research Group of Molecular Organized Systems, MPI for biophysical chemistry, Max Planck Society;

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Citation

Kozarac, Z., Dhathathreyan, A., & Möbius, D. (1988). Interaction of insulin with lipid monolayers at the air/solution interface. Colloids and Surfaces, 33(1-2), 11-24. doi:10.1016/0166-6622(88)80044-1.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002D-4CF2-3
Abstract
Interactions of insulin with lipid monolayers at the air/solution interface were studied by observing the kinetics of surface pressure change in the lipid monolayers at constant area and by spectroscopic techniques. The strong binding of insulin to positively-charged lipid monolayer resulted in increased surface pressure values, as well as in enhanced absorption and reflection signals in comparison to all other investigated lipid systems. This indicates that electrostatic interactions dominate these interactions.