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Do multigene families regulate vertebrate development?

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Dressler,  G.R.
Department of Molecular Cell Biology, MPI for biophysical chemistry, Max Planck Society;

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Gruss,  P.
Department of Molecular Cell Biology, MPI for biophysical chemistry, Max Planck Society;

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Citation

Dressler, G., & Gruss, P. (1988). Do multigene families regulate vertebrate development? Trends in Genetics, 4(8), 214-219. doi:10.1016/S0168-9525(88)80003-9.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002D-4D33-7
Abstract
The identification of mammalian gene families sharing protein domains with genes that regulate Drosophila embryogenesis could prove to be a major stepping stone towards understanding the genetic basis of mammalian development. Three types of multigene families have already been identified whose expression patterns during embryogenesis are strikingly different from one another. Evidence is accumulating that these multigene families may participate in pattern formation and segmentation of the mammalian embryo.