Ion exchanger from pearl-shaped cellulose gel

Determann, H.; Meyer, N.; Wieland, Theodor

doi:10.1038/223499a0

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Ion exchanger from pearl-shaped cellulose gel

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Determann, H.
Max Planck Institute for Medical Research, Max Planck Society;

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Wieland, Theodor
Max Planck Institute for Medical Research, Max Planck Society;

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Determann, H., Meyer, N., & Wieland, T. (1969). Ion exchanger from pearl-shaped cellulose gel. Nature, 223, 499-500. doi:10.1038/223499a0.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002D-7776-2

Abstract

WE have described a cellulose gel which allows chromatographic separation of mixtures of high molecular weight substances1. It was obtained from cellulose solutions suspended as droplets in an organic solvent. These beads have a rigid structure and they permit diffusion of very large molecules. We also prepared basic and acidic derivatives as possible ion exchangers for proteins. For this purpose cellulose was reacted with 1-chloro-2-diethyl-amino-ethane, α-chloroacetate or propane-sultone.