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Phalloidin poisoning of the isolated rat liver at 40°C

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Jahn,  Werner
Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

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Citation

Jahn, W. (1972). Phalloidin poisoning of the isolated rat liver at 40°C. Naunyn-Schmiedebergs Archives of Pharmacology, 274(1), 110-112. doi:10.1007/BF00501012.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002D-9519-C
Abstract
The first effect of phalloidin on the potassium content of the isolated liver is a small potassium uptake or a decrease of the spontaneous potassium release. This occurs at 40°C as well as at 27°C. At 40°C the potassium release due to phalloidin starts 14±3 min after the toxin has come in contact with the liver, while the increase of the weight, of the light scattering, and of the oxygen consumption of the liver start 10–12 min earlier.