Synthetic vaccines against Streptococcus pneumoniae serotype 2

Seeberger, Peter H.; Pereira, Claney Lebev; Chakkumkal, Anish; Khan, Naeem; Emmadi, Madhu

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特許

Synthetic vaccines against Streptococcus pneumoniae serotype 2

MPS-Authors

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Seeberger, Peter H.
Peter H. Seeberger, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Pereira, Claney Lebev
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

/persons/resource/persons121100

Chakkumkal, Anish
Chakkumal Anish, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Khan, Naeem
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Emmadi, Madhu
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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2475476.pdf
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引用

Khan, N., & Emmadi, M.(2017). Synthetic vaccines against Streptococcus pneumoniae serotype 2.

引用: https://hdl.handle.net/11858/00-001M-0000-002D-E07E-8

要旨

The present invention relates to a synthetic saccharide of general formula (I) that is related to Streptococcus pneumoniae serotype 2 capsular polysaccharide, a conjugate thereof and the use of said saccharide and conjugate for raising a protective immune response in a human and/or animal host. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Streptococcus pneumoniae type 2 bacteria. Another aspect of the present invention is directed to an antibody having specificity for a synthetic saccharide of general formula (I).