English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Journal Article

Interaction of phalloidin with actin

MPS-Authors
/persons/resource/persons206494

Lengsfeld,  Anneliese
Max Planck Institute for Medical Research, Max Planck Society;

/persons/resource/persons197059

Löw,  Irmentraut
Max Planck Institute for Medical Research, Max Planck Society;

/persons/resource/persons197838

Wieland,  Theodor
Max Planck Institute for Medical Research, Max Planck Society;

/persons/resource/persons205722

Dancker,  Peter
Max Planck Institute for Medical Research, Max Planck Society;

/persons/resource/persons93324

Hasselbach,  Wilhelm
Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

External Resource

http://www.pnas.org/content/71/7/2803.full.pdf
(Any fulltext)

Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Lengsfeld, A., Löw, I., Wieland, T., Dancker, P., & Hasselbach, W. (1974). Interaction of phalloidin with actin. Proceedings of the National Academy of Sciences of the United States of America, 71(7), 2803-2807. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/4368830.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002D-E265-C
Abstract
Phalloidin, a toxic bicyclic peptide of rapid action from the toadstool, Amanita phalloides, gives rise to polymerization of G-actin to filamentous structures (Ph-actin) in a medium of low ionic strength. Ph-actin closely resembles the microfilaments found in liver membrane fractions (Ph-filaments) after in vivo or in vitro poisoning. Both phalloidin induced filaments are resistant to 0.6 M KI in contrast to F-actin, and become decorated by heavy meromyosin. After preincubation with cytochalasin B significantly fewer actin filaments are observed.