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A combined recording and microiontophoresis technique for input-output analysis of single neurons in the mammalian CNS.

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Vahle-Hinz,  C.
Abteilung Neurobiologie, MPI for biophysical chemistry, Max Planck Society;

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Citation

Gottschaldt, K. M., Hicks, T. P., & Vahle-Hinz, C. (1988). A combined recording and microiontophoresis technique for input-output analysis of single neurons in the mammalian CNS. Journal of Neuroscience Methods, 23(3), 233-239. doi:10.1016/0165-0270(88)90007-6.


Cite as: https://hdl.handle.net/11858/00-001M-0000-002D-E6F4-6
Abstract
A method is described for producing electrolytically sharpened and lacquer-insulated steel microelectrodes and for their attachment to a multibarrel micropipet assembly by light-curing bonding compound. This electrode complex is specially designed for recordings from deep brain structures. It permits the analysis of the input signals to and the output signals from a single neuron recorded simultaneously from an extracellular electrode position, termed juxtacellular recording. Furthermore it provides the ability to manipulate pharmacologically the input-output ratio expressed by the neuron under varying sequences of natural stimulation.