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Semisynthetic biogenic magnetosome nanoparticles for the detection of proteins and nucleic acids

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Lang,  C.
Department of Microbiology, Max Planck Institute for Marine Microbiology, Max Planck Society;

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Schüler,  D.
Department of Microbiology, Max Planck Institute for Marine Microbiology, Max Planck Society;

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Citation

Ceyhan, B., Alhorn, P., Lang, C., Schüler, D., & Niemeyer, C. M. (2006). Semisynthetic biogenic magnetosome nanoparticles for the detection of proteins and nucleic acids. Small, 2(11), 1251-1255.


Cite as: http://hdl.handle.net/21.11116/0000-0001-CF02-4
Abstract
An attractive approach: Biogenic magnetic nanoparticles, so‐called magnetosomes, containing a magnetic iron oxide core enclosed in a protein–lipid membrane, were chemically functionalized with DNA oligonucleotides by using a modular coupling approach. The resulting nanoparticles were used for the assembly of heterostructures with DNA‐modified gold nanoparticles (see TEM image) and as reagents for protein detection.