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Aerosol health effects from molecular to global scales.

MPS-Authors
/persons/resource/persons101196

Pozzer,  Andrea
Atmospheric Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons101095

Lammel,  Gerhard
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons140326

Kampf,  Christopher J.
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons100944

Fröhlich-Nowoisky,  Janine
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons192195

Lakey,  Pascale S. J.
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons101104

Lelieveld,  Jos
Atmospheric Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons187669

Lucas,  Kurt
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons101189

Pöschl,  Ulrich
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons192191

Tong,  Haijie
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons133115

Weber,  Bettina
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

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Citation

Shiraiwa, M., Ueda, K., Pozzer, A., Lammel, G., Kampf, C. J., Fushimi, A., et al. (2017). Aerosol health effects from molecular to global scales. Environmental Science & Technology, 51(23), 13545-13567. doi:10.1021/acs.est.7b04417.


Cite as: http://hdl.handle.net/11858/00-001M-0000-002E-2A7D-E
Abstract
Poor air quality is the globally largest environmental health risk. Epidemiological studies have uncovered clear relationships of gaseous pollutants and particulate matter (PM) with adverse health outcomes, including mortality by cardiovascular and respiratory diseases. Studies of health impacts by aerosols are highly multidisciplinary with a broad range of scales in space and time. We assess recent advances and future challenges regarding aerosol effects on health from molecular to global scales, through epidemiological studies, field measurements, health-related properties of PM, and multiphase interactions of oxidants and PM upon respiratory deposition. Global modeling combined with epidemiological exposure-response functions indicates that ambient air pollution causes more than four million premature deaths per year. Epidemiological studies usually refer to PM mass concentrations, but some health effects may relate to specific constituents such as bioaerosols, polycyclic aromatic compounds, and transition metals. Various analytical techniques, cellular and molecular assays are applied to assess the redox activity of PM and the formation of reactive oxygen species. Multiphase chemical interactions of lung antioxidants with atmospheric pollutants are crucial to the mechanistic and molecular understanding of oxidative stress upon respiratory deposition. The role of distinct PM components in health impacts and mortality needs to be clarified by integrated research on various spatiotemporal scales for better evaluation and mitigation of aerosol effects on public health in the Anthropocene.