Rethinking functional segregation: Gradients of gene expression in area CA1

Tushev, Georgi; Schuman, Erin M.

doi:10.1016/j.neuron.2016.01.002

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Rethinking functional segregation: Gradients of gene expression in area CA1

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Tushev, Georgi
Synaptic Plasticity Department, Max Planck Institute for Brain Research, Max Planck Society;

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Schuman, Erin M.
Synaptic Plasticity Department, Max Planck Institute for Brain Research, Max Planck Society;

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https://pubmed.ncbi.nlm.nih.gov/26796687/
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Citation

Tushev, G., & Schuman, E. M. (2016). Rethinking functional segregation: Gradients of gene expression in area CA1. Neuron, 89, 242-243. doi:10.1016/j.neuron.2016.01.002.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002E-58D7-2

Abstract

An emerging view, based on gene expression patterns, is that discrete cell types occupy different regions in the hippocampus. In this issue of Neuron, Cembrowski et al. (2016) challenge this concept by identifying gradients of gene expression that suggest a molecular continuum of excitatory neurons and provide insights for organizational motifs at hippocampal poles.