Sulfur-containing compounds from the roots of Ferula latisecta and their 
cytotoxic activities

Soltani, Saba; Amin, Gholam-Reza; Salehi-Sourmaghi, Mohammad Hossein; Schneider, Bernd; Lorenz, Sybille; Iranshahi, Mehrdad

doi:10.1016/j.fitote.2017.10.012

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Sulfur-containing compounds from the roots of Ferula latisecta and their cytotoxic activities

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Schneider, Bernd
Research Group Biosynthesis / NMR, MPI for Chemical Ecology, Max Planck Society;

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Lorenz, Sybille
Research Group Mass Spectrometry, MPI for Chemical Ecology, Max Planck Society;

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Citation

Soltani, S., Amin, G.-R., Salehi-Sourmaghi, M. H., Schneider, B., Lorenz, S., & Iranshahi, M. (2018). Sulfur-containing compounds from the roots of Ferula latisecta and their cytotoxic activities. Fitoterapia, 124, 108-112. doi:10.1016/j.fitote.2017.10.012.

Cite as: https://hdl.handle.net/11858/00-001M-0000-002E-99B9-A

Abstract

Five new sulfur-containing compounds, with a new geometry (cis) of the propenyl moiety, and five known compounds were isolated from the roots of Ferula latisecta. The structures of these compounds, were elucidated on the basis of spectroscopic data including 1D and 2D NMR experiments and HRMS. All of the isolated compounds were tested against A2780, A549, HeLa, and HCT116 human cancer cell lines and some of them showed moderate cytotoxic activities.