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A miniaturized NMR-MOUSE with a high magnetic field gradient (Mini-MOUSE)


Glöggler,  S.
Research Group of NMR Signal Enhancement, MPI for Biophysical Chemistry, Max Planck Society;

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Oligschläger, D., Glöggler, S., Watzlaw, J., Brendel, K., Jaschtschuk, D., Colell, J., et al. (2015). A miniaturized NMR-MOUSE with a high magnetic field gradient (Mini-MOUSE). Applied Magnetic Resonance, 46(2), 181-202. doi:10.1007/s00723-014-0626-3.

Mobile nuclear magnetic resonance sensors still suffer from relatively high weight and large dimensions, although they are already considerably smaller than superconducting high-field magnets. Application of such sensors for an accurate analysis of rigid materials and thin layers is limited by the echo time of the radiofrequency (rf) coil and the spatial resolution of the sensor. This study presents the construction of a miniaturized NMR-MOUSE® that is reduced to about 90 % in volume and weight compared to a standard Profile NMR-MOUSE®. Thanks to the short dead time of 4 µs of the micro-structured rf coil, short transverse relaxation times of rigid and dry materials can be determined with improved accuracy. Furthermore, it is possible to record depth profiles with high resolution. The large magnetic field gradient of the new set-up leads to enhanced diffusion contrast.